Yamamoto Nutrition Liposomal Iron 30 caps

Ferro Fosfolipidico Lipofer™ is a dietary supplement containing 30 mg of LIPOFER™ microcapsules per daily dose. Iron contributes to the normal formation of red blood cells and hemoglobin* as well as the normal transport of oxygen in the body*. The product is enriched with vitamin C, which increases iron absorption.

Anemia is a very common problem affecting both men and women at various ages, but it is especially common in women of reproductive age. There are several different types of anemia, some of which may be temporary, while others are chronic with various characteristics. Anemia occurs when the hemoglobin concentration in the blood is less than 14 g/dl in men and less than 12 g/dl in women, and the number of red blood cells decreases below 4.5 x 10^6 / µl. To determine the state of anemia, a simple blood test is required, examining the following parameters:

• Complete blood count: a method to calculate the number and size of hemoglobin, red blood cells, and reticulocytes (immature red blood cells), as well as the number and type of white blood cells.
• Ferritin: the body's iron stores.
• Serum iron: the total amount of iron circulating in the blood.
• Transferrin: a protein that transports iron from the intestine and liver to tissues where it is needed.

Hemoglobin, a protein circulating in the blood, performs the function of transporting oxygen from the lungs to various body tissues and is also a major component of red blood cells. Low hemoglobin levels mean less oxygen supply to tissues, and since oxygen is essential for energy production, this causes feelings of fatigue and weakness. People with hemoglobin deficiency often also have reduced myoglobin, a protein responsible for transporting oxygen to muscles, including the heart, further increasing feelings of fatigue and shortness of breath. Poor oxygen supply causes peripheral vasoconstriction, which reduces blood flow to the extremities (especially hands and feet) to ensure a higher oxygen supply to vital organs. Therefore, people with anemia are more sensitive to cold.

Hemoglobin is also responsible for the bright red color of blood and tissues – if hemoglobin levels in the blood are low, the skin may appear paler. Oxygen deficiency in the blood forces the heart to work harder than usual to ensure the minimum required oxygen supply to all tissues, which also increases the heart rate. For example, especially young students need to consider that lower hemoglobin levels also result in reduced oxygen supply to the brain, so the brain may not function at maximum efficiency, leading to asthenia, apathy, sudden mood swings, and depressive states.

Women of reproductive age with heavy menstruation, as well as pregnant women or those with impaired iron absorption, are most susceptible to anemia. After eliminating any serious pathological problems that caused anemia and need to be properly managed, there is often a "procedure," both with a family doctor and independently, to periodically take iron supplements along with iron-containing foods. However, in many cases, blood parameters remain abnormal, and periodic courses of iron supplements are not tolerated by everyone due to numerous and frequent side effects such as nausea, digestive disorders like diarrhea or constipation, or dark stools, which often can even lead to discontinuation of treatment.

For this reason, research has sought the possibility of delivering iron supplements in liposomal form, such as our Ferro Fosfolipidico, which allows more efficient absorption of this valuable element without side effects and guarantees excellent bioavailability. Note that ionic iron is mainly absorbed in the duodenum and is transported through specific carriers. Under normal conditions, only 15-20% of ingested iron is absorbed, and even dietary iron has quite low bioavailability. A special encapsulation technology in natural phospholipids makes iron highly bioavailable, well tolerated, and rapidly absorbed. Liposomal protection protects iron from contact with the stomach lining, avoiding the oxidative effect caused by free iron. Liposomal protection allows the valuable micronutrient to pass through the stomach environment intact and be absorbed throughout the small intestine, not just in the duodenum.

Delivery via liposomal technology corresponds to the transport of various substances in our body through chylomicrons, which are lipoproteins representing the form of dietary fat transport from the intestine to various tissues. Orally administered iron liposome in the intestinal lumen is absorbed directly by M cells (not enterocytes), which originate from the lymphatic system and are found throughout the small intestine. The liposome is then assimilated by macrophages through endocytosis and reaches hepatocytes via the lymphatic flow.

The liposome is broken down in hepatocytes by lysosomal enzymes, thus providing LIPOFER™ iron to the body, ensuring liposomal iron absorption and bioavailability, which is higher than other iron salts widely used and present on the market for many years. Ferro Fosfolipidico is formulated with microencapsulated iron pyrophosphate in liposomal form (Lipofer™) with added Vitamin C to further increase mineral absorption and bioavailability, ensuring more effective integration and almost complete absence of common side effects.